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Deleterious effects of intravenous verapamil in Wolff-Parkinson-White patients and atrial fibrillation

Identifieur interne : 002841 ( Main/Exploration ); précédent : 002840; suivant : 002842

Deleterious effects of intravenous verapamil in Wolff-Parkinson-White patients and atrial fibrillation

Auteurs : Boris Strasberg [Israël] ; Alex Sagie [Israël] ; Eldad Rechavia [Israël] ; Amos Katz [Israël] ; A. Ovsyscher [Israël] ; Samuel Sclarovsky [Israël] ; Jacob Agmon [Israël]

Source :

RBID : ISTEX:F092A042232366C3AC33F4E3868688F296404F29

Abstract

Summary: Three patients presented to the emergency room with atrial fibrillation and fast ventricular response with wide preexcited QRS complexes (Wolff-Parkinson-White syndrome). All three patients received intravenous verapamil (5–10mg). The first patient developed ventricular fibrillation requiring several defibrillations; the second patient developed severe hemodynamic deterioration requiring urgent cardioversion; in the third patient a marked increment in the ventricular response was noted, however, there was no hemodynamic impairment. Verapamil may cause detrimental results when given to patients with the Wolff-Parkinson-White syndrome and atrial fibrillation. Its administration should therefore be considered as an absolute contraindication in these patients.

Url:
DOI: 10.1007/BF00133211


Affiliations:


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Le document en format XML

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<div type="abstract" xml:lang="en">Summary: Three patients presented to the emergency room with atrial fibrillation and fast ventricular response with wide preexcited QRS complexes (Wolff-Parkinson-White syndrome). All three patients received intravenous verapamil (5–10mg). The first patient developed ventricular fibrillation requiring several defibrillations; the second patient developed severe hemodynamic deterioration requiring urgent cardioversion; in the third patient a marked increment in the ventricular response was noted, however, there was no hemodynamic impairment. Verapamil may cause detrimental results when given to patients with the Wolff-Parkinson-White syndrome and atrial fibrillation. Its administration should therefore be considered as an absolute contraindication in these patients.</div>
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